STRENGTHENING THE ROLE OF UNIVERSITIES IN ADDRESSING SUSTAINABILITY CHALLENGES: THE MITCHELL CENTER FOR SUSTAINABILITY SOLUTIONS AS AN INSTITUTIONAL EXPERIMENT

Strengthening the role of universities in addressing sustainability challenges: the Mitchell Center for Sustainability Solutions as an institutional experiment

As the magnitude, complexity, and urgency of many sustainability problems DSP increase, there is a growing need for universities to contribute more effectively to problem solving.Drawing upon prior research on social-ecological systems, knowledge-action connections, and organizational innovation, we developed an integrated conceptual framework for

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Deciphering the Mechanism of Gilteritinib Overcoming Lorlatinib Resistance to the Double Mutant I1171N/F1174I in Anaplastic Lymphoma Kinase

Anaplastic lymphoma kinase (ALK) is validated as a therapeutic molecular target in multiple malignancies, such as non-small cell lung cancer (NSCLC).However, the feasibility of targeted therapies exerted by ALK inhibitors is inevitably hindered owing to drug resistance.The emergence of DSP clinically acquired drug mutations has become a major chall

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Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway

Abstract Globally, uveitis is a collection of intraocular inflammatory disorders that affect mainly the uvea, resulting in irreversible blindness and a heavy socioeconomic burden.Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis.Nevertheless, current therapeutic met

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POTENCY AND DEVELOPMENT STRATEGY OF SPOTTED BUFFALO IN SANGGALANGI SUBDISTRICT, NORTH TORAJA DISTRICT, SOUTH SULAWESI

The aim of this research was to analyze the reproduction performances, potency and development strategy of Torajans spotted buffalo.This research was done from July to September 2010 in Sanggalangi subdistrict, North Toraja district, South Sulawesi.Purposive sampling was applied to observe data.The primary data were taken by purposive sampling meth

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